Compound Detail
CHEMBL5963539
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Basic Information
| ChEMBL ID | CHEMBL5963539 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | LJSQXZZXHDYJEY-ZSOXZCCMSA-N |
1
Targets
3
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
361.4
MW (Da)
1.73
ALogP
5
HBA
2
HBD
103.5
PSA (Ų)
0.82
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 3 meas. best 9.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Interleukin-1 receptor-associated kinase 4 CHEMBL3778 | IC50 | 9.0 | 9.0 | 1.0 | 3 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Interleukin-1 receptor-associated kinase 4 | IC50 | = | 1.0 | nM | 9.0 | IRAK4 Enzymatic DELFIA Assay, Protocol A: This is an in vitro assay to measure I... | - |
| Interleukin-1 receptor-associated kinase 4 | IC50 | = | 1.0 | nM | 9.0 | Enzymatic DELFIA Assay: Protocol B: To begin the assay, 45 μL of reaction mixtur... | - |
| Interleukin-1 receptor-associated kinase 4 | IC50 | = | 1.0 | nM | 9.0 | IRAK4 Enzymatic DELFIA Assay, Protocol A: This is an in vitro assay to measure I... | - |
Data from ChEMBL 36 via Core Engine