Compound Detail
CHEMBL5968423
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Basic Information
| ChEMBL ID | CHEMBL5968423 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | GBAHBSLKOOONMN-LBPRGKRZSA-N |
2
Targets
8
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
279.3
MW (Da)
0.47
ALogP
3
HBA
1
HBD
66.6
PSA (Ų)
0.87
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 8 meas. best 6.89
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Dipeptidyl peptidase 8 CHEMBL4657 | IC50 | 6.89 | 6.89 | 128.0 | 1 |
| Dipeptidyl peptidase 9 CHEMBL4793 | IC50 | 4.27 | 4.27 | 53200.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Dipeptidyl peptidase 8 | IC50 | = | 128.0 | nM | 6.89 | EnPlex (purified enzyme activity assay): This assay is described in Bachovchin e... | - |
| Dipeptidyl peptidase 9 | IC50 | = | 53200.0 | nM | 4.27 | In Vitro Inhibition Assay: EnzymesRecombinant human DPPIV (R&D Systems, Cat. No.... | - |
Data from ChEMBL 36 via Core Engine