Compound Detail
CHEMBL5970436
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
CC(=O)c1ccc(NC(=O)Nc2ccc3c(c2)C(=O)N(CCc2c[nH]cn2)C(c2ccc(C#N)cc2)C3)cc1
Basic Information
| ChEMBL ID | CHEMBL5970436 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | RLPOHZHEPHEMIA-UHFFFAOYSA-N |
1
Targets
3
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
518.6
MW (Da)
5.11
ALogP
5
HBA
3
HBD
131.0
PSA (Ų)
0.29
QED
2
Ro5 Violations
7
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 3 meas. best 7.96
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| N-formyl peptide receptor 2 CHEMBL4227 | EC50 | 7.96 | 6.96 | 11.0 | 3 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| N-formyl peptide receptor 2 | EC50 | = | 11.0 | nM | 7.96 | FLIPR: HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Ce... | - |
| N-formyl peptide receptor 2 | EC50 | = | 11.0 | nM | 7.96 | FLIPR: HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Ce... | - |
| N-formyl peptide receptor 2 | EC50 | = | 11000.0 | nM | 4.96 | FLIPR: HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Ce... | - |
Data from ChEMBL 36 via Core Engine