N-formyl peptide receptor 2 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt P25090. Use UniProt P25090 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P25090 as the stable identity anchor, then attach disease evidence before program review.
N-formyl peptide receptor 2
Review this target as N-formyl peptide receptor 2, mapped to UniProt P25090. Sequence length is 351 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats N-formyl peptide receptor 2 as ChEMBL target CHEMBL4227, mapped to UniProt P25090. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | N-formyl peptide receptor 2 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P25090 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | N-formyl peptide receptor 2 |
| UniProt Accession | P25090 |
| Component Type | Protein |
| Sequence Length | 351 aa |
N-formyl peptide receptor 2
Review this target as N-formyl peptide receptor 2, mapped to UniProt P25090. Sequence length is 351 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5556956 | 11.0 | EC50 | 0.01 | Preclinical |
| CHEMBL5271637 | 10.7 | EC50 | 0.02 | Preclinical |
| CHEMBL4776349 | 10.3 | EC50 | 0.05 | Preclinical |
| CHEMBL5268572 | 10.3 | IC50 | 0.05 | Preclinical |
| CHEMBL552527 | 10.15 | EC50 | 0.07 | Preclinical |
| CHEMBL3730217 | 10.15 | EC50 | 0.07 | Preclinical |
| CHEMBL5567819 | 10.15 | EC50 | 0.07 | Preclinical |
| CHEMBL4790836 | 10.11 | EC50 | 0.078 | Preclinical |
| CHEMBL5542293 | 10.11 | EC50 | 0.077 | Preclinical |
| CHEMBL4743917 | 10.07 | EC50 | 0.085 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 73 | 480 | 7.8 |
| single protein format | 22 | 560 | 7.1 |
| assay format | 8 | 434 | 7.4 |
| cell membrane format | 1 | 19 | 6.7 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 61 | 705 | 7.0 |
| assay format | 12 | 80 | 6.9 |
| single protein format | 4 | 8 | 6.2 |