Compound Detail
CHEMBL59799
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Basic Information
| ChEMBL ID | CHEMBL59799 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | IQGLGXDCPZEOFC-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
317.3
MW (Da)
3.90
ALogP
3
HBA
1
HBD
54.9
PSA (Ų)
0.78
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.52
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 6.52 | 6.52 | 300.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 300.0 | nM | 6.52 | In vitro inhibition of Ab formation from trinitrophenyl-lipopolysaccharide (TNP-... | 11384243 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 11384243 | 10.1021/jm010822m | Mus musculus | 14 |
| 30108871 | 10.1039/C7MD00213K | Fibroblast growth factor receptor 4 | 3 |
| 11384243 | 10.1021/jm010822m | Unchecked | 1 |
| 11384243 | 10.1021/jm010822m | Jurkat | 1 |
Data from ChEMBL 36 via Core Engine