Compound Detail
CHEMBL5983536
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N#Cc1ccc(S(=O)(=O)N2C[C@H](S(=O)(=O)c3ccc(C(F)(F)F)cc3)[C@](O)(CO)C2)c(CO)c1
Basic Information
| ChEMBL ID | CHEMBL5983536 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | GBHDSGHULXRYJZ-RBUKOAKNSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
520.5
MW (Da)
0.64
ALogP
8
HBA
3
HBD
156.0
PSA (Ų)
0.50
QED
1
Ro5 Violations
6
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.26
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Transient receptor potential cation channel subfamily V member 4 CHEMBL3119 | IC50 | 7.26 | 7.26 | 55.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Transient receptor potential cation channel subfamily V member 4 | IC50 | = | 55.0 | nM | 7.26 | FLIPR Assay for hTRPV4 Expressed in BHK Cells: TRPV4 channel activation results ... | - |
Data from ChEMBL 36 via Core Engine