Compound Detail
CHEMBL5984035
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Basic Information
| ChEMBL ID | CHEMBL5984035 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | WFQAMUFXBXJWTQ-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
456.5
MW (Da)
3.08
ALogP
7
HBA
1
HBD
75.0
PSA (Ų)
0.64
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 2 meas. best 8.64
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Interleukin-1 receptor-associated kinase 4 CHEMBL3778 | Ki | 8.64 | 8.11 | 2.3 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Interleukin-1 receptor-associated kinase 4 | Ki | = | 2.3 | nM | 8.64 | Biological Assay: Kinase activities were assayed using the Transcreener-Fluorece... | - |
| Interleukin-1 receptor-associated kinase 4 | Ki | = | 26.0 | nM | 7.58 | Biological Assay: Kinase activities were assayed using the Transcreener-Fluorece... | - |
Data from ChEMBL 36 via Core Engine