Compound Detail
CHEMBL5987182
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL5987182 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | VUDMYIHKNCGYRY-UHFFFAOYSA-N |
3
Targets
3
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
381.4
MW (Da)
3.22
ALogP
6
HBA
3
HBD
129.2
PSA (Ų)
0.41
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 3 meas. best 8.21
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Fibroblast growth factor receptor 2 CHEMBL4142 | IC50 | 8.21 | 8.21 | 6.2 | 1 |
| Fibroblast growth factor receptor 1 CHEMBL3650 | IC50 | 8.05 | 8.05 | 9.0 | 1 |
| Fibroblast growth factor receptor 3 CHEMBL2742 | IC50 | 7.5 | 7.5 | 32.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Fibroblast growth factor receptor 2 | IC50 | = | 6.2 | nM | 8.21 | Inhibition Kinase Activity Assay: The FGFR2 inhibitory activities of compounds l... | - |
| Fibroblast growth factor receptor 1 | IC50 | = | 9.0 | nM | 8.05 | Inhibition Kinase Activity Assay: The FGFR1 inhibitory activities of compounds w... | - |
| Fibroblast growth factor receptor 3 | IC50 | = | 32.0 | nM | 7.5 | Inhibition Kinase Activity Assay: The FGFR3 inhibitory activities of compounds l... | - |
Data from ChEMBL 36 via Core Engine