Compound Detail
CHEMBL5988064
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL5988064 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | PUTIJCKMSRBHDZ-UHFFFAOYSA-N |
3
Targets
3
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
350.4
MW (Da)
2.97
ALogP
6
HBA
2
HBD
96.5
PSA (Ų)
0.59
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 3 meas. best 5.3
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Mitogen-activated protein kinase 8 CHEMBL2276 | IC50 | 5.3 | 5.3 | 5050.0 | 1 |
| Mitogen-activated protein kinase 10 CHEMBL2637 | IC50 | 5.3 | 5.3 | 5050.0 | 1 |
| Mitogen-activated protein kinase 9 CHEMBL4179 | IC50 | 5.3 | 5.3 | 5050.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Mitogen-activated protein kinase 10 | IC50 | = | 5050.0 | nM | 5.3 | HTRF Assay: (1) Assay buffer #1 with 0.0025% Tween and 1 mM DTT was prepared usi... | - |
| Mitogen-activated protein kinase 8 | IC50 | = | 5050.0 | nM | 5.3 | HTRF Assay: (1) Assay buffer #1 with 0.0025% Tween and 1 mM DTT was prepared usi... | - |
| Mitogen-activated protein kinase 9 | IC50 | = | 5050.0 | nM | 5.3 | HTRF Assay: (1) Assay buffer #1 with 0.0025% Tween and 1 mM DTT was prepared usi... | - |
Data from ChEMBL 36 via Core Engine