Compound Detail
CHEMBL6000207
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL6000207 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | NXJRHBCZVUMYJV-UHFFFAOYSA-N |
2
Targets
3
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
414.4
MW (Da)
2.89
ALogP
8
HBA
1
HBD
108.5
PSA (Ų)
0.50
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 3 meas. best 8.2
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Histone acetyltransferase KAT6A CHEMBL3774298 | Ki | 8.2 | 8.045 | 6.2 | 2 |
| Histone acetyltransferase KAT7 CHEMBL3774299 | Ki | 6.66 | 6.66 | 220.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Histone acetyltransferase KAT6A | Ki | = | 6.25 | nM | 8.2 | Kat6A Assay 2: A. Compound preparation 1. Prepare 10 mM stock solutions in 10... | - |
| Histone acetyltransferase KAT6A | Ki | = | 13.0 | nM | 7.89 | Kat6A Assay 1: A. Compound preparation 1. Prepare 10 mM stock solutions in 10... | - |
| Histone acetyltransferase KAT7 | Ki | = | 220.0 | nM | 6.66 | Kat7 Assay: A. Compound preparation 1. Prepare 10 mM stock solutions in 100% ... | - |
Data from ChEMBL 36 via Core Engine