Compound Detail
CHEMBL6000290
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
CCOC(=O)c1cncc(-c2ccc(CNC(=O)C3C[C@H]3c3ccccc3)c3c2CCN(C(=O)NC(C)(C)C)C3)c1
Basic Information
| ChEMBL ID | CHEMBL6000290 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | CYIXPMIDGDCYSG-MBMZGMDYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
554.7
MW (Da)
5.21
ALogP
5
HBA
2
HBD
100.6
PSA (Ų)
0.39
QED
2
Ro5 Violations
7
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 9.18
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Diacylglycerol O-acyltransferase 2 CHEMBL5853 | IC50 | 9.18 | 9.18 | 0.7 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Diacylglycerol O-acyltransferase 2 | IC50 | = | 0.66 | nM | 9.18 | Enzymatic Activity Assay: DGAT2 activity was determined by measuring the amount ... | - |
Data from ChEMBL 36 via Core Engine