Compound Detail
CHEMBL6005367
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Basic Information
| ChEMBL ID | CHEMBL6005367 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | PXFDARHZNBYXBD-UHFFFAOYSA-N |
2
Targets
3
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
443.5
MW (Da)
5.33
ALogP
7
HBA
2
HBD
107.5
PSA (Ų)
0.36
QED
1
Ro5 Violations
4
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 3 meas. best 6.03
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Platelet-derived growth factor receptor beta CHEMBL1913 | IC50 | 6.03 | 6.03 | 936.0 | 2 |
| Vascular endothelial growth factor receptor 2 CHEMBL279 | IC50 | 6.03 | 6.03 | 936.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Vascular endothelial growth factor receptor 2 | IC50 | = | 936.0 | nM | 6.03 | Biochemical Assay: Biochemical KDR kinase assays were performed in 96 well micro... | - |
| Platelet-derived growth factor receptor beta | IC50 | = | 936.0 | nM | 6.03 | Kinase Assay: PDGFRβ: Biochemical PDGFRβ kinase assays were performed in 96 well... | - |
| Platelet-derived growth factor receptor beta | IC50 | = | 936.0 | nM | 6.03 | PDGFRbeta Kinase Assay: Biochemical PDGFRβ kinase assays were performed in 96 we... | - |
Data from ChEMBL 36 via Core Engine