Compound Detail
CHEMBL6007636
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Basic Information
| ChEMBL ID | CHEMBL6007636 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | NJIPWDMSPZHCTE-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
411.5
MW (Da)
4.15
ALogP
7
HBA
1
HBD
71.8
PSA (Ų)
0.53
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 8.57
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Activin receptor type-1 CHEMBL5903 | IC50 | 8.57 | 8.025 | 2.7 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Activin receptor type-1 | IC50 | = | 2.7 | nM | 8.57 | Enzyme Inhibitory Assay: R206H: An overview of evaluation of an inhibitory effec... | - |
| Activin receptor type-1 | IC50 | = | 33.0 | nM | 7.48 | Enzyme Inhibitory Assay: TABLE 5: An overview of evaluation of an inhibitory eff... | - |
Data from ChEMBL 36 via Core Engine