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Compound Detail

CHEMBL6015867

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CCCN1CCC[C@@H]2Cc3c(ccc(O)c3O[C@@H]3O[C@H](C(=O)O)[C@@H](O)[C@H](O)[C@H]3O)C[C@H]21

Basic Information

ChEMBL ID CHEMBL6015867
Phase Preclinical
Structure Type MOL
InChI Key UAFMEIHFRQARQG-VFUBLZDWSA-N
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

437.5
MW (Da)
0.25
ALogP
8
HBA
5
HBD
139.9
PSA (Ų)
0.44
QED
0
Ro5 Violations
5
Rot. Bonds

Drug Information

Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C22H31NO8
MW 437.49
Aromatic Rings 1
Heavy Atoms 31
NP-Likeness 1.50

Activity Summary

EC50 2 meas. best 5.96

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
D(2) dopamine receptor
CHEMBL217
EC50 5.96 5.96 1100.0 1
D(1A) dopamine receptor
CHEMBL2056
EC50 5.57 5.57 2700.0 1

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine