Compound Detail
CHEMBL6019285
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
CCn1cc(-c2ccnc(Nc3ccc(N4CCN(CC5CCOC5)CC4)cc3)n2)c(-c2cccnc2)n1
Basic Information
| ChEMBL ID | CHEMBL6019285 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DZGVKQPOHKGHRJ-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
510.6
MW (Da)
4.32
ALogP
9
HBA
1
HBD
84.2
PSA (Ų)
0.38
QED
1
Ro5 Violations
8
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.84
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Activin receptor type-1 CHEMBL5903 | IC50 | 7.84 | 7.84 | 14.3 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Activin receptor type-1 | IC50 | = | 14.3 | nM | 7.84 | Enzyme Inhibitory Assay: R206H: An overview of evaluation of an inhibitory effec... | - |
Data from ChEMBL 36 via Core Engine