Compound Detail
CHEMBL6026429
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL6026429 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | XMAKRWBDDLFCDV-NSHDSACASA-N |
2
Targets
3
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
430.4
MW (Da)
3.48
ALogP
9
HBA
1
HBD
95.0
PSA (Ų)
0.53
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 3 meas. best 10.06
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Mitogen-activated protein kinase 1 CHEMBL4040 | IC50 | 10.06 | 10.06 | 0.1 | 2 |
| Mitogen-activated protein kinase 6 CHEMBL5121 | IC50 | 9.78 | 9.78 | 0.2 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Mitogen-activated protein kinase 1 | IC50 | = | 0.088 | nM | 10.06 | Enzymatic Assay: Compounds were tested in an enzymatic assay using human ERK-2 (... | - |
| Mitogen-activated protein kinase 1 | IC50 | = | 0.088 | nM | 10.06 | ERK-2 Enzymatic Assay: Compounds were tested in an enzymatic assay using human E... | - |
| Mitogen-activated protein kinase 6 | IC50 | = | 0.168 | nM | 9.78 | Enzymatic Assay: Compounds were tested in an enzymatic assay using human ERK-2 (... | - |
Data from ChEMBL 36 via Core Engine