Compound Detail
CHEMBL6027874
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
CC1(C)CC=C(c2nc(C3CC(C)(C)OC(C)(C(=O)OO)C3)ccc2NC(=O)c2nc(C#N)c[nH]2)CC1
Basic Information
| ChEMBL ID | CHEMBL6027874 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | CQVMBRZRVCWMST-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
507.6
MW (Da)
4.97
ALogP
8
HBA
3
HBD
150.2
PSA (Ų)
0.38
QED
1
Ro5 Violations
5
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 8.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Macrophage colony-stimulating factor 1 receptor CHEMBL1844 | IC50 | 8.0 | 8.0 | 10.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Macrophage colony-stimulating factor 1 receptor | IC50 | = | 10.0 | nM | 8.0 | Human c-Fms Protein Kinase Assay (gamma-33P-ATP Format): c-fms(h) was incubated ... | - |
Data from ChEMBL 36 via Core Engine