Compound Detail
CHEMBL6028431
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Basic Information
| ChEMBL ID | CHEMBL6028431 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | XPTFPKBOFBPFSV-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
484.0
MW (Da)
5.26
ALogP
7
HBA
3
HBD
106.6
PSA (Ų)
0.45
QED
1
Ro5 Violations
5
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.56
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Vascular endothelial growth factor receptor 2 CHEMBL279 | IC50 | 5.56 | 5.56 | 2750.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Vascular endothelial growth factor receptor 2 | IC50 | = | 2750.0 | nM | 5.56 | Test of Small Molecule Compounds for Inhibiting the Activity of VEGFR-2 Kinase: ... | - |
Data from ChEMBL 36 via Core Engine