Compound Detail
CHEMBL6028619
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Basic Information
| ChEMBL ID | CHEMBL6028619 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | HVXIUQPPMQEORQ-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
407.4
MW (Da)
2.08
ALogP
6
HBA
2
HBD
106.6
PSA (Ų)
0.79
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 9.22
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Alkaline phosphatase, tissue-nonspecific isozyme CHEMBL5979 | IC50 | 9.22 | 9.22 | 0.6 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Alkaline phosphatase, tissue-nonspecific isozyme | IC50 | = | 0.6 | nM | 9.22 | TNAP Inhibition Activity: COS 1 cells (DS Pharma Biomedical Co., Ltd.) were tran... | - |
| Alkaline phosphatase, tissue-nonspecific isozyme | IC50 | = | 0.6 | nM | 9.22 | Inhibitory Test of TNAP Activity: COS1 cells (DS Pharma Biomedical Co., Ltd.) we... | - |
Data from ChEMBL 36 via Core Engine