Compound Detail
CHEMBL6034599
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Basic Information
| ChEMBL ID | CHEMBL6034599 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | VYVMTNNUVNSRBD-UHFFFAOYSA-N |
3
Targets
4
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
293.4
MW (Da)
3.37
ALogP
2
HBA
1
HBD
31.9
PSA (Ų)
0.75
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Kd 4 meas. best 9.01
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Microtubule-associated protein tau CHEMBL1293224 | Kd | 9.01 | 9.01 | 1.0 | 1 |
| Unchecked CHEMBL612545 | Kd | 8.92 | 8.92 | 1.2 | 1 |
| Alpha-synuclein CHEMBL6152 | Kd | 8.62 | 8.62 | 2.4 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Microtubule-associated protein tau | Kd | = | 0.97 | nM | 9.01 | In Vitro Direct Determination By Fluorescence: Table 6 & 7: Fresh solutions of e... | - |
| Unchecked | Kd | = | 1.2 | nM | 8.92 | In Vitro Direct Determination By Fluorescence: Table 6 & 7: Fresh solutions of e... | - |
| Alpha-synuclein | Kd | = | 2.4 | nM | 8.62 | In Vitro Direct Determination By Fluorescence: Table 6 & 7: Fresh solutions of e... | - |
| Alpha-synuclein | Kd | = | 2.4 | nM | 8.62 | In Vitro Direct Determination By Fluorescence: Table 6 & 7: Fresh solutions of e... | - |
Data from ChEMBL 36 via Core Engine