Compound Detail
CHEMBL6041362
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Basic Information
| ChEMBL ID | CHEMBL6041362 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | CPVRDKGAKOBBHQ-SWLSCSKDSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
368.4
MW (Da)
2.13
ALogP
6
HBA
1
HBD
100.3
PSA (Ų)
0.76
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 7.26
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| High affinity nerve growth factor receptor CHEMBL2815 | IC50 | 7.26 | 6.89 | 55.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| High affinity nerve growth factor receptor | IC50 | = | 55.0 | nM | 7.26 | Enzyme Assay: In each well of a 384-well plate, 1 nM-1.5 nM of wild type NTRK1 e... | - |
| High affinity nerve growth factor receptor | IC50 | = | 300.0 | nM | 6.52 | NTRK1 Wild Type Assay at 1 mM ATP: In each well of a 384-well plate, 1 nM-1.5 nM... | - |
Data from ChEMBL 36 via Core Engine