Compound Detail
CHEMBL6042375
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CO[C@@H]1CCN(c2cc(NC(=O)N3CCCc4cc(CN5CCCCOC5=O)c(C=O)nc43)ncc2C#N)C1
Basic Information
| ChEMBL ID | CHEMBL6042375 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | BIRXBGBZGNCPSH-OAQYLSRUSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
533.6
MW (Da)
3.10
ALogP
9
HBA
1
HBD
141.0
PSA (Ų)
0.55
QED
1
Ro5 Violations
6
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 8.54
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Fibroblast growth factor receptor 4 CHEMBL3973 | IC50 | 8.54 | 8.54 | 2.9 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Fibroblast growth factor receptor 4 | IC50 | = | 2.89 | nM | 8.54 | Enzymologic Experiment of FGFR4: In this experiment, the inhibitory effect of th... | - |
Data from ChEMBL 36 via Core Engine