Compound Detail
CHEMBL6047714
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Basic Information
| ChEMBL ID | CHEMBL6047714 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | HBALAPRVSOJBQZ-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
468.6
MW (Da)
4.87
ALogP
8
HBA
2
HBD
97.8
PSA (Ų)
0.40
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 8.52
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Activin receptor type-1 CHEMBL5903 | IC50 | 8.52 | 8.49 | 3.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Activin receptor type-1 | IC50 | = | 3.0 | nM | 8.52 | Enzyme Inhibitory Assay: R206H: An overview of evaluation of an inhibitory effec... | - |
| Activin receptor type-1 | IC50 | = | 3.5 | nM | 8.46 | Enzyme Inhibitory Assay: TABLE 5: An overview of evaluation of an inhibitory eff... | - |
Data from ChEMBL 36 via Core Engine