Compound Detail
CHEMBL6055810
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Basic Information
| ChEMBL ID | CHEMBL6055810 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | JVPBPORZRDYLOU-FXQIFTODSA-N |
5
Targets
12
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
230.1
MW (Da)
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 12 meas. best 7.96
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Dipeptidyl peptidase 9 CHEMBL4793 | IC50 | 7.96 | 6.46 | 11.0 | 2 |
| Dipeptidyl peptidase 8 CHEMBL4657 | IC50 | 7.62 | 6.12 | 24.0 | 2 |
| Unchecked CHEMBL612545 | IC50 | 6.0 | 6.0 | 1000.0 | 1 |
| Dipeptidyl peptidase 4 CHEMBL284 | IC50 | 5.05 | 5.05 | 9000.0 | 1 |
| Prolyl endopeptidase FAP CHEMBL4683 | IC50 | 4.12 | 4.12 | 75000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Dipeptidyl peptidase 9 | IC50 | = | 11.0 | nM | 7.96 | EnPlex (purified enzyme activity assay): This assay is described in Bachovchin e... | - |
| Dipeptidyl peptidase 8 | IC50 | = | 24.0 | nM | 7.62 | EnPlex (purified enzyme activity assay): This assay is described in Bachovchin e... | - |
| Unchecked | IC50 | = | 1000.0 | nM | 6.0 | EnPlex (purified enzyme activity assay): This assay is described in Bachovchin e... | - |
| Dipeptidyl peptidase 4 | IC50 | = | 9000.0 | nM | 5.05 | In Vitro Inhibition Assay: EnzymesRecombinant human DPPIV (R&D Systems, Cat. No.... | - |
| Dipeptidyl peptidase 9 | IC50 | = | 11000.0 | nM | 4.96 | In Vitro Inhibition Assay: EnzymesRecombinant human DPPIV (R&D Systems, Cat. No.... | - |
| Dipeptidyl peptidase 8 | IC50 | = | 24000.0 | nM | 4.62 | In Vitro Inhibition Assay: EnzymesRecombinant human DPPIV (R&D Systems, Cat. No.... | - |
| Prolyl endopeptidase FAP | IC50 | = | 75000.0 | nM | 4.12 | In Vitro Inhibition Assay: EnzymesRecombinant human DPPIV (R&D Systems, Cat. No.... | - |
Data from ChEMBL 36 via Core Engine