Compound Detail
CHEMBL605877
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Basic Information
| ChEMBL ID | CHEMBL605877 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | JUJHLFFBRZXSTL-WIUUEXBZSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
260.2
MW (Da)
-2.67
ALogP
6
HBA
5
HBD
122.5
PSA (Ų)
0.38
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 6.4
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Cytidine deaminase CHEMBL2110 | Ki | 6.4 | 6.4 | 400.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Cytidine deaminase | Ki | = | 400.0 | nM | 6.4 | Compound was tested for the inhibitory constant for mouse kidney cytidine deamin... | 3735306 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 3735306 | 10.1021/jm00158a009 | Cytidine deaminase | 1 |
| 3735306 | 10.1021/jm00158a009 | L1210 | 1 |
Data from ChEMBL 36 via Core Engine