Compound Detail
CHEMBL6063419
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
C=CCn1c(=O)c2cnc(Nc3ccc(N4CCN[C@H](COC)C4)cc3)nc2n1-c1cccc(N=S(C)(C)=O)n1
Basic Information
| ChEMBL ID | CHEMBL6063419 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | QEWVMCKPZXJERR-FQEVSTJZSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
563.7
MW (Da)
2.69
ALogP
12
HBA
2
HBD
131.6
PSA (Ų)
0.30
QED
2
Ro5 Violations
9
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 9.22
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Wee1-like protein kinase CHEMBL5491 | IC50 | 9.22 | 9.22 | 0.6 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Wee1-like protein kinase | IC50 | = | 0.6 | nM | 9.22 | Kinase Activity Assay: All reactions took place in 60 μL volumes in reaction buf... | - |
Data from ChEMBL 36 via Core Engine