Compound Detail
CHEMBL6063716
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Basic Information
| ChEMBL ID | CHEMBL6063716 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | KLDIXBATHFTXDM-UHFFFAOYSA-N |
3
Targets
3
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
480.4
MW (Da)
3.49
ALogP
9
HBA
1
HBD
117.7
PSA (Ų)
0.39
QED
0
Ro5 Violations
9
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 3 meas. best 9.44
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Histone acetyltransferase KAT6A CHEMBL3774298 | Ki | 9.44 | 9.44 | 0.4 | 1 |
| Histone acetyltransferase KAT6B CHEMBL3774300 | Ki | 9.44 | 9.44 | 0.4 | 1 |
| Histone acetyltransferase KAT7 CHEMBL3774299 | Ki | 6.64 | 6.64 | 230.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Histone acetyltransferase KAT6A | Ki | = | 0.36 | nM | 9.44 | Kat6A Assay 1: A. Compound preparation 1. Prepare 10 mM stock solutions in 10... | - |
| Histone acetyltransferase KAT6B | Ki | = | 0.36 | nM | 9.44 | Kat6B Assay 2: A. Compound preparation 1. Prepare 10 mM stock solutions in 10... | - |
| Histone acetyltransferase KAT7 | Ki | = | 230.0 | nM | 6.64 | Kat7 Assay: A. Compound preparation 1. Prepare 10 mM stock solutions in 100% ... | - |
Data from ChEMBL 36 via Core Engine