Compound Detail
CHEMBL607293
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Basic Information
| ChEMBL ID | CHEMBL607293 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | MRZGFGZACXZCAM-GCEBAUNBSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
312.5
MW (Da)
3.71
ALogP
3
HBA
1
HBD
24.5
PSA (Ų)
0.90
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 5.07
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Sigma non-opioid intracellular receptor 1 CHEMBL287 | Ki | 5.07 | 5.07 | 8554.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Sigma non-opioid intracellular receptor 1 | Ki | = | 8554.0 | nM | 5.07 | Affinity for sigma receptor type 1 of guinea pig using [3H]ifenprodil or (+)-[3H... | 16033255 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 16033255 | 10.1021/jm049073+ | Sigma non-opioid intracellular receptor 1 | 1 |
Data from ChEMBL 36 via Core Engine