Compound Detail
CHEMBL608537
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Basic Information
| ChEMBL ID | CHEMBL608537 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | KAASYKNZNPWPQG-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
244.3
MW (Da)
2.81
ALogP
2
HBA
1
HBD
28.3
PSA (Ų)
0.90
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 6.2
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 7 CHEMBL3223 | Ki | 6.2 | 6.2 | 631.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 7 | Ki | = | 630.96 | nM | 6.2 | Binding affinity at rat 5-hydroxytryptamine 7 receptor. | 14640545 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 14640545 | 10.1021/jm030826m | 5-hydroxytryptamine receptor 7 | 2 |
Data from ChEMBL 36 via Core Engine