Compound Detail
CHEMBL608722
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL608722 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | WIZZRWWXSSWLEO-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
294.3
MW (Da)
2.84
ALogP
5
HBA
2
HBD
75.3
PSA (Ų)
0.57
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.76
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Phospholipase A-2-activating protein CHEMBL6114 | IC50 | 4.76 | 4.76 | 17200.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Phospholipase A-2-activating protein | IC50 | = | 17200.0 | nM | 4.76 | Inhibition of PLAP by analogous luminescence assay | 20031422 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 20031422 | 10.1016/j.bmc.2009.12.012 | Phospholipase A-2-activating protein | 1 |
| 20031422 | 10.1016/j.bmc.2009.12.012 | Alkaline phosphatase, tissue-nonspecific isozyme | 1 |
| 20031422 | 10.1016/j.bmc.2009.12.012 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine