Compound Detail
CHEMBL611034
DESMETHYLDEHYDROALTENUSIN Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL611034 |
| Name | DESMETHYLDEHYDROALTENUSIN |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | HKBOKSSAYTZITB-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
274.2
MW (Da)
1.43
ALogP
6
HBA
3
HBD
104.1
PSA (Ų)
0.62
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 6.05
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 6.05 | 6.05 | 890.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 890.0 | nM | 6.05 | Inhibition of calf thymus DNA polymerase alpha by [3H]dTTP incorporation assay | 19767211 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19767211 | 10.1016/j.bmc.2009.08.051 | Unchecked | 3 |
| 19767211 | 10.1016/j.bmc.2009.08.051 | DNA polymerase beta | 1 |
Data from ChEMBL 36 via Core Engine