Compound Detail
CHEMBL62570
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Basic Information
| ChEMBL ID | CHEMBL62570 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | GMVPRGQOIOIIMI-CHCORRSHSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
354.5
MW (Da)
3.48
ALogP
4
HBA
3
HBD
94.8
PSA (Ų)
0.35
QED
0
Ro5 Violations
13
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 2 meas. best 9.66
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Prostaglandin E2 receptor EP4 subtype CHEMBL1836 | EC50 | 9.66 | 9.66 | 0.2 | 1 |
| Prostaglandin E2 receptor EP2 subtype CHEMBL1881 | EC50 | 7.78 | 7.78 | 16.5 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Prostaglandin E2 receptor EP4 subtype | EC50 | = | 0.22 | nM | 9.66 | cAMP Assay: 1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,... | - |
| Prostaglandin E2 receptor EP2 subtype | EC50 | = | 16.5 | nM | 7.78 | SEAP Activity Assay: 1. Seed cells on an EP2 or EP4 STEP plate at a density of 4... | - |
Data from ChEMBL 36 via Core Engine