Compound Detail
CHEMBL63516
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Basic Information
| ChEMBL ID | CHEMBL63516 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UCYSIRDFOWPOOK-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
339.3
MW (Da)
2.03
ALogP
9
HBA
1
HBD
124.3
PSA (Ų)
0.45
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 7.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glutamate receptor ionotropic, AMPA CHEMBL2093871 | Ki | 7.0 | 7.0 | 99.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glutamate receptor ionotropic, AMPA | Ki | = | 99.0 | nM | 7.0 | The compound was tested for its ability to inhibit [3H]AMPA binding to Ionotropi... | 9207947 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 9207947 | 10.1021/jm960664c | Glutamate receptor ionotropic, AMPA | 1 |
Data from ChEMBL 36 via Core Engine