Compound Detail
CHEMBL65979
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Basic Information
| ChEMBL ID | CHEMBL65979 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | CMQWSHZUXWRMAJ-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
371.5
MW (Da)
4.33
ALogP
6
HBA
0
HBD
56.7
PSA (Ų)
0.69
QED
0
Ro5 Violations
8
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 5.66
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Corticotropin-releasing factor receptor 1 CHEMBL1800 | Ki | 5.66 | 5.66 | 2200.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Corticotropin-releasing factor receptor 1 | Ki | = | 2200.0 | nM | 5.66 | Binding affinity towards human Corticotropin releasing factor receptor 1 by the ... | 15080983 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 15080983 | 10.1016/j.bmcl.2004.02.053 | Corticotropin-releasing factor receptor 1 | 1 |
Data from ChEMBL 36 via Core Engine