Compound Detail
CHEMBL68686
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Basic Information
| ChEMBL ID | CHEMBL68686 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | LAHWVQFOBUUDBA-YHMJZVADSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
209.2
MW (Da)
0.09
ALogP
4
HBA
2
HBD
72.5
PSA (Ų)
0.69
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 2 meas. best 4.48
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Cytosol aminopeptidase CHEMBL3965 | Ki | 4.48 | 4.48 | 33000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Cytosol aminopeptidase | Ki | = | 33000.0 | nM | 4.48 | Inhibitory activity against Leucine aminopeptidase | 3184126 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 3184126 | 10.1021/jm00119a022 | Aminopeptidase N | 1 |
| 3184126 | 10.1021/jm00119a022 | Cytosol aminopeptidase | 1 |
| 3184126 | 10.1021/jm00119a022 | Aminopeptidase B | 1 |
Data from ChEMBL 36 via Core Engine