Compound Detail
CHEMBL68739
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL68739 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | BEPANIVQPGBOQX-WQRHYEAKSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
366.3
MW (Da)
5.67
ALogP
4
HBA
0
HBD
39.9
PSA (Ų)
0.65
QED
1
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.92
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Metabotropic glutamate receptor 2 CHEMBL2851 | IC50 | 5.92 | 5.92 | 1210.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Metabotropic glutamate receptor 2 | IC50 | = | 1210.0 | nM | 5.92 | Inhibition of 10 uM 1S, 3R-ACPD stimulated GTP gamma 35S binding to rat mGluR2 e... | 10465539 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 10465539 | 10.1016/s0960-894x(99)00346-7 | Metabotropic glutamate receptor 2 | 1 |
Data from ChEMBL 36 via Core Engine