Compound Detail
CHEMBL69441
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Basic Information
| ChEMBL ID | CHEMBL69441 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FTCVKDVKBLADDH-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
247.2
MW (Da)
-0.61
ALogP
6
HBA
2
HBD
90.4
PSA (Ų)
0.73
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| C8166 CHEMBL614533 | IC50 | 5.0 | 5.0 | 10000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| C8166 | IC50 | = | 10000.0 | nM | 5.0 | Antiviral activity against HIV-1 (RF strain) in C8166 cells | 2165161 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 2165161 | 10.1021/jm00170a015 | C8166 | 2 |
| 7520081 | 10.1021/jm00042a005 | Human immunodeficiency virus type 1 reverse transcriptase | 1 |
| 2165161 | 10.1021/jm00170a015 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine