Compound Detail
CHEMBL7352
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Basic Information
| ChEMBL ID | CHEMBL7352 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | SNNZHOLVTLIFSO-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
6
Publications
0
Known Names
Molecular Properties
389.4
MW (Da)
4.07
ALogP
6
HBA
3
HBD
88.7
PSA (Ų)
0.55
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 4.73
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 4.73 | 4.73 | 18500.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 18500.0 | nM | 4.73 | Inhibition of BALB/MK mouse epidermal keratinocyte proliferation | 8151612 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 8151612 | 10.1021/jm00033a019 | Epidermal growth factor receptor | 2 |
| 8151612 | 10.1021/jm00033a019 | Tyrosine-protein kinase ABL | 1 |
| 8151612 | 10.1021/jm00033a019 | Protein kinase C (PKC) | 1 |
| 8151612 | 10.1021/jm00033a019 | cAMP-dependent protein kinase alpha-catalytic subunit | 1 |
| 8151612 | 10.1021/jm00033a019 | Platelet-derived growth factor receptor | 1 |
| 8151612 | 10.1021/jm00033a019 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine