Compound Detail
CHEMBL73967
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Basic Information
| ChEMBL ID | CHEMBL73967 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | VNORITPQZHTCHX-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
216.3
MW (Da)
1.31
ALogP
3
HBA
1
HBD
35.2
PSA (Ų)
0.78
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 8.33
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 1A CHEMBL273 | Ki | 8.33 | 8.33 | 4.7 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 1A | Ki | = | 4.72 | nM | 8.33 | In vitro binding affinity towards 5-hydroxytryptamine 1A receptor was determined... | 10476865 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 10476865 | 10.1016/s0960-894x(99)00384-4 | 5-hydroxytryptamine receptor 1A | 1 |
| 20078106 | 10.1021/jm901672k | 5-hydroxytryptamine receptor 6 | 1 |
Data from ChEMBL 36 via Core Engine