Compound Detail
CHEMBL7727
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Basic Information
| ChEMBL ID | CHEMBL7727 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | OANFSEHROSIYSQ-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
176.2
MW (Da)
2.06
ALogP
2
HBA
1
HBD
29.5
PSA (Ų)
0.70
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.32
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Homo sapiens CHEMBL372 | IC50 | 6.32 | 6.32 | 480.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Homo sapiens | IC50 | = | 480.0 | nM | 6.32 | Inhibitory activity against Leukotriene (LTB4) biosynthesis in isolated human po... | 2709371 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 2709371 | 10.1021/jm00125a014 | Homo sapiens | 1 |
| 2709371 | 10.1021/jm00125a014 | No relevant target | 1 |
Data from ChEMBL 36 via Core Engine