Compound Detail
CHEMBL7790
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Basic Information
| ChEMBL ID | CHEMBL7790 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FWKXMJCJEOUXDE-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
284.3
MW (Da)
5.15
ALogP
2
HBA
2
HBD
40.5
PSA (Ų)
0.23
QED
1
Ro5 Violations
0
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Kd 1 meas. best 4.85
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Estrogen receptor CHEMBL2304421 | Kd | 4.85 | 4.85 | 14000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Estrogen receptor | Kd | = | 14000.0 | nM | 4.85 | Displacement of [3H]-estradiol (E2) from sheep uterine estrogen receptor | 14761204 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 14761204 | 10.1021/jm0309607 | Estrogen receptor | 1 |
| 10836148 | 10.1146/annurev.pharmtox.40.1.581 | UDP-glucuronosyltransferase 1-6 | 1 |
| 10836148 | 10.1146/annurev.pharmtox.40.1.581 | UDP-glucuronosyltransferase 2B7 | 1 |
Data from ChEMBL 36 via Core Engine