Compound Detail
CHEMBL78894
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL78894 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | IAPLTZHXXFXFMM-IFWOZUGISA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
328.4
MW (Da)
4.48
ALogP
3
HBA
2
HBD
49.7
PSA (Ų)
0.84
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.07
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Tubulin CHEMBL2111464 | IC50 | 6.07 | 6.07 | 850.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Tubulin | IC50 | = | 850.0 | nM | 6.07 | Inhibition of polymerization of purified bovine tubulin | 10882369 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 10882369 | 10.1021/jm0001119 | Cell line | 1 |
| 10882369 | 10.1021/jm0001119 | Tubulin | 1 |
Data from ChEMBL 36 via Core Engine