Compound Detail
CHEMBL80348
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Basic Information
| ChEMBL ID | CHEMBL80348 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | BSVJVOYGJXNOED-KNTRCKAVSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
285.4
MW (Da)
3.01
ALogP
4
HBA
2
HBD
70.5
PSA (Ų)
0.36
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 8.36
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Histamine H3 receptor CHEMBL4124 | Ki | 8.36 | 8.36 | 4.4 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Histamine H3 receptor | Ki | = | 4.4 | nM | 8.36 | In vitro inhibitory activity against Histamine H3 receptor for K+ evoked depolar... | 11055360 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 11055360 | 10.1016/s0960-894x(00)00473-x | Histamine H3 receptor | 2 |
Data from ChEMBL 36 via Core Engine