Compound Detail
CHEMBL87707
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Basic Information
| ChEMBL ID | CHEMBL87707 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DGTIEGLFCLUQEE-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
523.7
MW (Da)
7.93
ALogP
5
HBA
2
HBD
96.6
PSA (Ų)
0.11
QED
2
Ro5 Violations
17
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.6
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Homo sapiens CHEMBL372 | IC50 | 5.6 | 5.6 | 2500.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Homo sapiens | IC50 | = | 2500.0 | nM | 5.6 | Cytosolic phospholipase A2 (c-PLA2) inhibitory potency of the compound was evalu... | 11551751 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 11551751 | 10.1016/s0960-894x(01)00472-3 | Homo sapiens | 1 |
Data from ChEMBL 36 via Core Engine