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Compound Detail

CHEMBL95363

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CC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C=O)CCS(C)(=O)=O

Basic Information

ChEMBL ID CHEMBL95363
Phase Preclinical
Structure Type BOTH
InChI Key ZFGFVZBFASCKIP-ULQDDVLXSA-N
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names

Molecular Properties

433.6
MW (Da)
0.19
ALogP
6
HBA
3
HBD
138.5
PSA (Ų)
0.35
QED
0
Ro5 Violations
13
Rot. Bonds

Drug Information

Molecule Type Protein
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C19H35N3O6S
MW 433.57
Aromatic Rings 0
Heavy Atoms 29
NP-Likeness 0.15

Activity Summary

IC50 1 meas. best 4.09

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Human rhinovirus sp.
CHEMBL612470
IC50 4.09 4.09 81900.0 1

Activity Data Samples

Top measurements by pChEMBL value

Target Type Rel. Value Units pChEMBL Assay PubMed
Human rhinovirus sp. IC50 = 81900.0 nM 4.09 Antiviral activity against human rhinovirus-14 in HeLa cells -

Literature References

PubMed DOI Target Context # Activities
- 10.1016/S0960-894X(96)00537-9 Human rhinovirus sp. 1
- 10.1016/S0960-894X(96)00537-9 HeLa 1

Data from ChEMBL 36 via Core Engine