Compound Detail
CHEMBL97407
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL97407 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | JKQDAIVDZXQKCT-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
192.3
MW (Da)
3.00
ALogP
3
HBA
1
HBD
38.9
PSA (Ų)
0.75
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 4.05
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Sodium channel protein type 4 subunit alpha CHEMBL2072 | IC50 | 4.05 | 4.05 | 89000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Sodium channel protein type 4 subunit alpha | IC50 | = | 89000.0 | nM | 4.05 | Inhibition of human Nav 1.4 expressed in HEK293T cells assessed as phasic block ... | 37465302 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 37465302 | 10.1021/acsmedchemlett.3c00224 | Sodium channel protein type 4 subunit alpha | 2 |
| 10425092 | 10.1021/jm980202u | Rattus norvegicus | 1 |
| 10425092 | 10.1021/jm980202u | No relevant target | 1 |
| 37465302 | 10.1021/acsmedchemlett.3c00224 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine