Compound Detail
CHEMBL98723
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Basic Information
| ChEMBL ID | CHEMBL98723 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | BCLMRTYDVWUZQC-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
5
Publications
0
Known Names
Molecular Properties
252.2
MW (Da)
-0.26
ALogP
7
HBA
3
HBD
127.4
PSA (Ų)
0.68
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.13
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glutamate receptor ionotropic kainate CHEMBL2109241 | IC50 | 4.13 | 4.13 | 74000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glutamate receptor ionotropic kainate | IC50 | = | 74000.0 | nM | 4.13 | In vitro binding affinity against Ionotropic glutamate receptor kainate (kainic ... | 9288165 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 9288165 | 10.1021/jm970253b | Glutamate receptor ionotropic AMPA | 1 |
| 9288165 | 10.1021/jm970253b | Glutamate receptor ionotropic kainate | 1 |
| 9288165 | 10.1021/jm970253b | Glutamate [NMDA] receptor | 1 |
| 9288165 | 10.1021/jm970253b | Rattus norvegicus | 1 |
| 9288165 | 10.1021/jm970253b | No relevant target | 1 |
Data from ChEMBL 36 via Core Engine