Compound Detail
CHEMBL98806
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Basic Information
| ChEMBL ID | CHEMBL98806 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | VGWCIDBBQHNKMU-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
391.5
MW (Da)
5.62
ALogP
3
HBA
1
HBD
50.7
PSA (Ų)
0.40
QED
1
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.19
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Protein farnesyltransferase CHEMBL2094108 | IC50 | 7.19 | 7.19 | 65.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Protein farnesyltransferase | IC50 | = | 65.0 | nM | 7.19 | Inhibition of [3H]FPP incorporation into Ha-ras protein by Farnesyltransferase | 11677136 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 11677136 | 10.1016/s0960-894x(01)00593-5 | Protein farnesyltransferase | 1 |
Data from ChEMBL 36 via Core Engine