Compound Detail
CHEMBL9956
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Basic Information
| ChEMBL ID | CHEMBL9956 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | PURVSUKLCQURDE-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
467.5
MW (Da)
7.12
ALogP
4
HBA
0
HBD
41.9
PSA (Ų)
0.40
QED
1
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 7.6
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Corticotropin-releasing factor receptor 1 CHEMBL1800 | Ki | 7.6 | 7.6 | 24.9 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Corticotropin-releasing factor receptor 1 | Ki | = | 24.9 | nM | 7.6 | Displacement of [125I]-TYR-ovine CRH from cloned human corticotropin releasing f... | 10230640 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 10230640 | 10.1016/s0960-894x(99)00132-8 | Corticotropin-releasing factor receptor 1 | 1 |
Data from ChEMBL 36 via Core Engine