A-type voltage-gated potassium channel KCND2 · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-14Protein identity stays anchored to UniProt Q63881. Use UniProt Q63881 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q63881 as the stable identity anchor, then attach disease evidence before program review.
A-type voltage-gated potassium channel KCND2
Review this target as A-type voltage-gated potassium channel KCND2, mapped to UniProt Q63881. Sequence length is 630 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats A-type voltage-gated potassium channel KCND2 as ChEMBL target CHEMBL1075227, mapped to UniProt Q63881. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether A-type voltage-gated potassium channel KCND2 is the right protein anchor across sources, using UniProt Q63881 as the stable mapping.
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| Preferred Name | A-type voltage-gated potassium channel KCND2 |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | Q63881 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | A-type voltage-gated potassium channel KCND2 |
| UniProt Accession | Q63881 |
| Component Type | Protein |
| Sequence Length | 630 aa |
A-type voltage-gated potassium channel KCND2
Review this target as A-type voltage-gated potassium channel KCND2, mapped to UniProt Q63881. Sequence length is 630 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1294 | 5.66 | IC50 | 2200.0 | Approved |
| CHEMBL229125 | 5.05 | IC50 | 8900.0 | Preclinical |
| CHEMBL375475 | 5.05 | IC50 | 9000.0 | Preclinical |
| CHEMBL652 | 5.0 | IC50 | 10100.0 | Approved |
| CHEMBL387935 | 4.96 | IC50 | 11000.0 | Preclinical |
| CHEMBL387671 | 4.77 | IC50 | 17000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 1 | 7 | 5.1 |